New Protein Target in Prostate Cancer

Researchers at Boston University School of Medicine have found a protein that is related to the growth of prostate cancer, BRD4. By inhibiting this protein cancer growth was slowed, opening a new potential avenue to new medicines that can target this protein. The work has been done under the supervision of Gerald Denis, PhD. Similar findings in other cancers have led to ground-breaking new drug therapies. It will be many years before this work evolves to therapeutic alternatives, but it is promising.

See the actual paper: Jordan S. Shafran, Guillaume P. Andrieu, Balazs Gyorffy, Gerald V. Denis. BRD4 regulates metastatic potential of castration-resistant prostate cancer through AHNAKMolecular Cancer Research, 2019; molcanres.1279.2018 DOI: 10.1158/1541-7786.MCR-18-1279

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