{"id":431,"date":"2020-10-10T21:12:38","date_gmt":"2020-10-10T21:12:38","guid":{"rendered":"https:\/\/www.atkinsonurology.com\/journal\/?p=431"},"modified":"2020-10-10T21:14:49","modified_gmt":"2020-10-10T21:14:49","slug":"new-protein-target-in-prostate-cancer","status":"publish","type":"post","link":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/","title":{"rendered":"New Protein Target in Prostate Cancer"},"content":{"rendered":"\n<p>Researchers at Boston University School of Medicine have found a protein that is related to the growth of prostate cancer, BRD4.  By inhibiting this protein cancer growth was slowed, opening a new potential avenue to new medicines that can target this protein.  The work has been done under the supervision of Gerald Denis, PhD.  Similar findings in other cancers have led to ground-breaking new drug therapies.  It will be many years before this work evolves to therapeutic alternatives, but it is promising.<\/p>\n\n\n\n<p>See the actual paper: Jordan S. Shafran, Guillaume P. Andrieu, Balazs Gyorffy, Gerald V. Denis.\u00a0<strong>BRD4 regulates metastatic potential of castration-resistant prostate cancer through AHNAK<\/strong>.\u00a0<em>Molecular Cancer Research<\/em>, 2019; molcanres.1279.2018 DOI:\u00a0<a href=\"http:\/\/dx.doi.org\/10.1158\/1541-7786.MCR-18-1279\" rel=\"noreferrer noopener\" target=\"_blank\">10.1158\/1541-7786.MCR-18-1279<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at Boston University School of Medicine have found a protein that is related to the growth of prostate cancer, BRD4.  By inhibiting this protein cancer growth was slowed, opening a new potential avenue to new medicines that can target this protein.  The work has been done under the supervision of Gerald Denis, [<a href=\"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/\">read more&#8230;<\/a>]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[44,45,36],"class_list":["post-431","post","type-post","status-publish","format-standard","hentry","category-prostate-cancer","tag-brd4","tag-gerald-denis","tag-prostate-cancer"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>New Protein Target in Prostate Cancer &#060; J. Dudley Atkinson IV, MD - Urologist in Fargo<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New Protein Target in Prostate Cancer &#060; J. Dudley Atkinson IV, MD - Urologist in Fargo\" \/>\n<meta property=\"og:description\" content=\"Researchers at Boston University School of Medicine have found a protein that is related to the growth of prostate cancer, BRD4. By inhibiting this protein cancer growth was slowed, opening a new potential avenue to new medicines that can target this protein. The work has been done under the supervision of Gerald Denis, [read more...]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/\" \/>\n<meta property=\"og:site_name\" content=\"J. Dudley Atkinson IV, MD - Urologist in Fargo\" \/>\n<meta property=\"article:published_time\" content=\"2020-10-10T21:12:38+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2020-10-10T21:14:49+00:00\" \/>\n<meta name=\"author\" content=\"Dudley Atkinson\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Dudley Atkinson\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"New Protein Target in Prostate Cancer &#060; J. Dudley Atkinson IV, MD - Urologist in Fargo","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/","og_locale":"en_US","og_type":"article","og_title":"New Protein Target in Prostate Cancer &#060; J. Dudley Atkinson IV, MD - Urologist in Fargo","og_description":"Researchers at Boston University School of Medicine have found a protein that is related to the growth of prostate cancer, BRD4. By inhibiting this protein cancer growth was slowed, opening a new potential avenue to new medicines that can target this protein. The work has been done under the supervision of Gerald Denis, [read more...]","og_url":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/","og_site_name":"J. Dudley Atkinson IV, MD - Urologist in Fargo","article_published_time":"2020-10-10T21:12:38+00:00","article_modified_time":"2020-10-10T21:14:49+00:00","author":"Dudley Atkinson","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Dudley Atkinson","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/#article","isPartOf":{"@id":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/"},"author":{"name":"Dudley Atkinson","@id":"https:\/\/www.atkinsonurology.com\/journal\/#\/schema\/person\/acf7d54ff39025ee5e2e66fd119531a8"},"headline":"New Protein Target in Prostate Cancer","datePublished":"2020-10-10T21:12:38+00:00","dateModified":"2020-10-10T21:14:49+00:00","mainEntityOfPage":{"@id":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/"},"wordCount":121,"publisher":{"@id":"https:\/\/www.atkinsonurology.com\/journal\/#\/schema\/person\/acf7d54ff39025ee5e2e66fd119531a8"},"keywords":["brd4","gerald denis","Prostate Cancer"],"articleSection":["Prostate Cancer"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/","url":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/","name":"New Protein Target in Prostate Cancer &#060; J. Dudley Atkinson IV, MD - Urologist in Fargo","isPartOf":{"@id":"https:\/\/www.atkinsonurology.com\/journal\/#website"},"datePublished":"2020-10-10T21:12:38+00:00","dateModified":"2020-10-10T21:14:49+00:00","breadcrumb":{"@id":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.atkinsonurology.com\/journal\/2020\/10\/new-protein-target-in-prostate-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.atkinsonurology.com\/journal\/"},{"@type":"ListItem","position":2,"name":"Prostate Cancer","item":"https:\/\/www.atkinsonurology.com\/journal\/category\/prostate-cancer\/"},{"@type":"ListItem","position":3,"name":"New Protein Target in Prostate Cancer"}]},{"@type":"WebSite","@id":"https:\/\/www.atkinsonurology.com\/journal\/#website","url":"https:\/\/www.atkinsonurology.com\/journal\/","name":"J. Dudley Atkinson IV, MD - Urologist in Fargo","description":"Urologist in Fargo","publisher":{"@id":"https:\/\/www.atkinsonurology.com\/journal\/#\/schema\/person\/acf7d54ff39025ee5e2e66fd119531a8"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.atkinsonurology.com\/journal\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":["Person","Organization"],"@id":"https:\/\/www.atkinsonurology.com\/journal\/#\/schema\/person\/acf7d54ff39025ee5e2e66fd119531a8","name":"Dudley Atkinson","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.atkinsonurology.com\/journal\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/b6a2ca0b8801ca7c8c59be91e038b1fe?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/b6a2ca0b8801ca7c8c59be91e038b1fe?s=96&d=mm&r=g","caption":"Dudley Atkinson"},"logo":{"@id":"https:\/\/www.atkinsonurology.com\/journal\/#\/schema\/person\/image\/"},"sameAs":["https:\/\/www.atkinsonurology.com"]}]}},"_links":{"self":[{"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/posts\/431"}],"collection":[{"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/comments?post=431"}],"version-history":[{"count":2,"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/posts\/431\/revisions"}],"predecessor-version":[{"id":433,"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/posts\/431\/revisions\/433"}],"wp:attachment":[{"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/media?parent=431"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/categories?post=431"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.atkinsonurology.com\/journal\/wp-json\/wp\/v2\/tags?post=431"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}