FAQs about Testosterone

What is testosterone replacement therapy?

Testosterone can be given a patient with low testosterone due to primary testicular failure. The methods vary, but include oral agents, injections, patches, and gels. Oral agents are consumed quickly by the liver, so high doses are needed. Intramuscular injections have the benefit of lasting longer as depot injections can slowly be activated by the body, allowing normal levels to last as long as a month after an initial peak. Patches are adequate but sometimes cause skin irritation. Gels are relatively new but are effective, but caution is needed to prevent getting the gel on anything other than the patients own skin. Also available are pellets that are injected under the skin. Which choice depends on the patient and individual goals of therapy.

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